Cold plasma affects the body at once with a whole complex of chemically active particles, photons, as well as charged particles and an electric field. Each of these components has a bactericidal effect or leads to cell stimulation. Plasma in a cold state has not only bactericidal properties, but also contributes to the destruction of substances hazardous to health (in water and air). These properties of the gas have become widespread (with the aim of restoring the condition of the skin) in the field of cosmetology.
Numerous experiments have proved that cold plasma has valuable properties with great potential for application: bactericidal, fungicidal and antiviral effects, destruction of biofilms.

Histological studies by Kilmer et al. 2007 showed regenerative activity in the epidermis and dermis, collagen remodeling, activation of neocollagenesis and neoelastogenesis.

There’s also positive effect of cold plasma on the process of wound healing and skin regeneration. After plasma treatment, the number of galectins increased (Akimoto et al 2016), and two minutes of wound treatment resulted in a significant decrease in the number of both gram-negative and gram-positive bacteria (Isbary et al. 2012).

There are three main effects that provide a positive result:

The first effect is the heating of the protein structures of the skin, which leads to the appearance of a tension vector and diffuse tightening in a radius of 0.1-0.3 cm around the impact of the impulse. The result is visible immediately after the procedure, which highlights the cold plasma method on the positive side.
The second effect is a consequence of the first – in the area of ​​exposure to cold plasma, collagen and elastin proteins are denatured, giving the effect of retraction (diffuse tightening). The body seeks to restore the optimal number of collagen structures and begins active synthesis of new collagen and elastin in the affected area. Young molecules strengthen the already “taut” framework, increasing the density of the skin.
Complete maturation of collagen and elastin fibers occurs within 4-12 weeks. Since the formed protein molecules have a spiral structure, additional retraction (lifting) occurs.
The third effect is a response to thermal injury: instead of temperature-damaged cells – epidermal cells, the body urgently “gives out” a pool of new cells: it starts the maturation of dormant undifferentiated cells into specialized cells that produce collagen, elastin and are responsible for other functions.
Cell maturation occurs within 4-12 weeks. The final effect of the cold plasma procedure will appear after 3 months and will consist in renewing the skin of the affected area at the cellular level.


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